6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline
(R)-6,7-dimethoxy-4-(3-(quinoxalin-2-yloxy)pyrrolidin-1-yl)quinazoline
CAS: 927691-21-2
Molecular Formula: C22H21N5O3
6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline - Names and Identifiers
6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline - Physico-chemical Properties
| Molecular Formula | C22H21N5O3 |
| Molar Mass | 403.43 |
| Density | 1.333 |
| Solubility | Soluble in DMSO |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | 2-8°C |
| Use | PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker. |
| Target | PDE10A |
6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline - Risk and Safety
| WGK Germany | 3 |
6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline - Reference
| Reference Show more | Single-Use Polymer Membrane-Based Polyion-Sensitive Electrodes. ACS Sens. 2017 Feb 24;2(2):268-273. doi: 10.1021/acssensors.6b00787. Epub 2017 Jan 23. PubMed PMID: 28723131.5: Breviglieri E, Mota da Silva L, Boeing T, Somensi LB, Cury BJ, Gimenez A, Cechinel Filho V, de Andrade SF. Gastroprotective and anti-secretory mechanisms of 2-phenylquinoline, an alkaloid isolated from Galipea longiflora. Phytomedicine. 2017 Feb 15;25:61-70. doi: 10.1016/j.phymed.2016.12.016. Epub 2016 Dec 24. PubMed PMID: 28190472.6: Tang SP, Kuttulebbai Nainamohamed Salam S, Jaafar H, Gan SH, Muzaimi M, Sulaiman SA. Tualang Honey Protects the Rat Midbrain and Lung against Repeated Paraquat Exposure. Oxid Med Cell Longev. 2017;2017:4605782. doi: 10.1155/2017/4605782. Epub 2017 Jan 3. PubMed PMID: 28127418; PubMed Central PMCID: PMC5239975.7: Ferguson SA, Wang X, Meyerhoff ME. Detecting Levels of Polyquaternium-10 (PQ-10) via Potentiometric Titration with Dextran Sulphate and Monitoring the Equivalence Point with a Polymeric Membrane-Based Polyion Sensor. Anal Methods. 2016 Aug 7;8(29):5806-5811. doi: 10.1039/C6AY01748G. Epub 2016 Jul 4. PubMed PMID: 28018490; PubMed Central PMCID: PMC5176107.8: Novaes RD, Gonçalves RV, Cupertino MC, Santos EC, Bigonha SM, Fernandes GJ, Maldonado IR, Natali AJ. Acute paraquat exposure determines dose-dependent oxidative injury of multiple organs and metabolic dysfunction in rats: impact on exercise tolerance. Int J Exp Pathol. 2016 Apr;97(2):114-24. doi: 10.1111/iep.12183. Epub |
6,7-dimethoxy-4-[3-(2-quinoxalinyloxy)-1-pyrrolidinyl]quinazoline - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.479 ml | 12.394 ml | 24.787 ml |
| 5 mM | 0.496 ml | 2.479 ml | 4.957 ml |
| 10 mM | 0.248 ml | 1.239 ml | 2.479 ml |
| 5 mM | 0.05 ml | 0.248 ml | 0.496 ml |
Last Update：2024-01-02 23:10:35
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Product Name: (R)-6,7-dimethoxy-4-(3-(quinoxalin-2-yloxy)pyrrolidin-1-yl)quinazoline Visit Supplier Webpage Request for quotationCAS: 927691-21-2
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